ABSTRACT
Objective: In this study our main objective is to evaluate therelationship between Oesophageal varices, Portal veindiameter and splenic length (antero-posterior).Methodology: This Cross-sectional comparative studyconducted at the Department of Hepatology, BangabandhuSheikh Mujib Medical University (BSMMU) from Jan 2010 toDec 2011 where 50 Patients with cirrhosis of liver attending thedepartment of Hepatology, BSMMU were included as apopulation in this study.All the data was checked and edited after collection. It wasexpressed as Mean and SD. Data has been analyzed byANOVA. p value of less than 0.05 was considered statisticallysignificant. Statistical analysis was done by using SPSS-15(Statistical package for social sciences) win version 15software programme.Results: During the study, the mean age was43.12±15.68years. The highest frequency of cirrhosis patientswas found in 41-50 years age groups (Frequency 12). Leadingcause was HBV (68%) followed by HCV (12%), NBNC (12%),Wilson’s disease (6%) and both HVB& HCV (2%). Also,grade-3 mean portal Vein diameter was found 12.67±2.47 mmwhereas; mean splenic length (antero-post.) was 13.82±2.12cm.Conclusion: Splenic antero-posterior measurement is not areliable predictor for sizes of oesophageal varices. Furtherstudy is needed for better outcome.
ABSTRACT
Background: Non-alcoholic fatty liver disease (NAFLD) is theterm for a range of situations caused by a build-up of fat inthe liver. It's usually seen in people who are obese.Objective: In this study our main goal is to evaluate theassociation of liver histology with sonological grading and liverstiffness measured by Fibroscan in patients with NAFLD.Methods: This cross-sectional study was done at Departmentof Hepatology, Bangabandhu Sheikh Mujib Medical Universityfrom July 2007 to June 2009. Total 45 patients of fatty liverdisease were studied. All collected data was recorded in astructured questionnaire and was analyzed by SPSS version20. Values were expressed either as mean + SD or infrequency or in percentages.Results: During the study majority of the patients were 30-50years old (73.33 %), which indicates that the patients weresomewhat younger and out of 45 of study population 21(46.7%) patients was grade I fatty liver, 23(51.1%) were gradeII fatty liver and only one (2.2%) was grade III fatty liver. Thisstudy also showed that correlation between fibroscan of liverand grading of fibrosis in liver histology reveals significantassociation.